• HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform

HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform

  • Up to 2 × Intel® Xeon® Scalable, 28 cores
  • Up to 3 TB DDR4-2933 ECC memory
  • Up to 24 + 6 SFF or 12 LFF hot-swap bays, NVMe/SAS/SATA mix
  • 3 × PCIe 3.0 slots  |  Embedded 4 × 1 GbE
  • Fully customizable Configure-To-Order (CTO) options
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform
  • HPE ProLiant DL388 Gen10 Rack Server | Enterprise Wholesale 2U CTO Platform

Description

Overview

What is your server bottleneck—storage, compute, expansion? The world’s best-selling platform just levelled-up. The HPE ProLiant DL388 Gen10 delivers leading-edge security, performance and expandability, all backed by HPE’s comprehensive warranty.

Standardise on the industry’s most trusted 2U compute: Intel® Xeon® Scalable processors (up to 71 % faster and 27 % more cores than the previous generation) and HPE DDR4 SmartMemory at 2666 MT/s (up to 3 TB) drive mission-critical workloads. The chassis supports 12 Gb/s SAS and up to 20 NVMe drives plus a broad range of PCIe options.

HPE Persistent Memory turbo-charges databases and analytics, while HPE iLO 5 and OneView automate deployment, monitoring and updates so you can run anything from entry VMs to real-time analytics with confidence.

What's New

  • Firmware-anchored security and optional chassis-intrusion detection
  • HPE Persistent Memory for breakthrough in-memory performance
  • Intelligent System Tuning for workload-optimised throughput
  • Modular drive backplanes — mix LFF, SFF and NVMe in one chassis
  • Full support for the latest Intel® Xeon® Scalable family

Product Series

SKU CPU / Memory Drive Bays Controller PSU Tier
868709-AA1 Xeon Bronze 3104 • 1 P • 16 GB 8 SFF S100i SATA RAID 1 × 500 W Entry
826564-AA1 Xeon Bronze 3106 • 1 P • 16 GB 8 SFF S100i SATA RAID 1 × 500 W Entry+
826565-AA1 Xeon Silver 4110 • 1 P • 32 GB 8 SFF P408i-a SAS RAID 1 × 500 W Base
826566-AA1 Xeon Silver 4114 • 1 P • 32 GB 8 SFF P408i-a SAS RAID 1 × 500 W Base+
Q9A02A Xeon Silver 4108 • 1 P • 16 GB 8 SFF P408i-a SAS RAID 1 × 500 W Base
Q9A03A Xeon Silver 4110 • 1 P • 16 GB 8 SFF P408i-a SAS RAID 1 × 500 W Base
Q9A04A Xeon Silver 4116 • 1 P • 32 GB 8 SFF P408i-a SAS RAID 1 × 500 W Performance
Q9A05A Xeon Silver 4114 • 1 P • 32 GB 8 SFF P408i-a SAS RAID 1 × 500 W Performance-
Q9A06A Xeon Gold 5118 • 1 P • 32 GB 8 SFF P408i-a SAS RAID 1 × 500 W Hi-Perf

CTO Chassis Options

SKU Front Bays Drive Type Height PCIe Slots
868703-B21 8 × SFF SAS / SATA / NVMe 2U 3 × Gen 3
868706-B21 8 × LFF SAS / SATA 2U 3 × Gen 3
868705-B21 12 × LFF SAS / SATA 2U 3 × Gen 3
868704-B21 24 × SFF SAS / SATA / NVMe 2U 3 × Gen 3

* All chassis ship with dual Smart-Socket CPU carriers, 24 DIMM slots, embedded S100i SATA RAID and iLO 5 management. Start here, then build your perfect DL380 Gen10 with our online configurator.

Key Features

Flexible, Scalable Design

A brand-new modular chassis supports up to 30 SFF, 19 LFF or 20 NVMe bays, plus up to 3 double-wide GPUs. Redesigned Smart Array controllers let you flip between SAS RAID and HBA mode to match any workload.

HPE Persistent Memory

Up to 192 GB of cache-class NVDIMMs accelerates analytics and databases, delivering 27× faster checkpoint and 20× faster restore operations than disk-based approaches.

Security Built In

  • Silicon Root of Trust anchors firmware directly in hardware
  • Run-Time Firmware Validation checks critical code every 24 h
  • Secure Recovery rolls back to a known-good image on detection of tampering
  • TPM 2.0 and chassis Intrusion Detection available

World-Class Performance

Intel® Xeon® Scalable CPUs (up to 28 cores) and up to 3 TB of DDR4-2933 SmartMemory boost throughput, while Intelligent System Tuning profiles shave latency for jitter-sensitive workloads.

Enterprise Services

HPE Pointnext delivers Advisory & Transformation, Professional and Operational Services — including Flexible Capacity, Datacenter Care and Proactive Services — to slash deployment risk and operating overhead.

Technical Specifications

Processor Family Intel® Xeon® Scalable 8100 / 6100 / 5100 / 4100 / 3100 Series
Cores per CPU 4 – 28 cores (model dependent)
Max Memory 3 TB (24 × 128 GB DDR4-2933 SmartMemory)
Up to 192 GB HPE Persistent Memory (NVDIMM)
Drive Bays 8 / 12 LFF SAS/SATA/SSD
8, 10, 16, 18 or 24 SFF SAS/SATA/SSD
Up to 20 NVMe SFF
Optional rear: 6 × SFF or 3 × LFF + 2 × SFF
Storage Controllers Embedded S100i plus optional P408i-a, P816i-a or E208i-a (model dependent)
Expansion Slots Up to 8 × PCIe 3.0
Network Embedded 4 × 1 GbE 331i
Optional FlexibleLOM / stand-up 1–40 GbE
Form Factor 2U rack
Power Supplies Up to 2 × Flex Slot (model dependent)
Cooling Hot-plug redundant fans
Dimensions (W × D × H) 44.54 × 67.94 × 8.73 cm (8 SFF)  /  44.54 × 73.02 × 8.73 cm (LFF)
Weight 32.6 lb (min, chassis only)
Management iLO Standard with Intelligent Provisioning; optional iLO Advanced / Premium Security Edition; OneView Standard / Advanced

Server Configuration

Build your custom DL380 Gen10 in seconds with our real-time configurator—every QuickSpecs option, instant pricing, automatic compatibility checks and live lead-time data – all verified by our technical team before shipment.

  • Full QuickSpecs database & instant BOM pricing
  • Component-level compatibility review on every order
  • Clear shipping costs and lead times up front

Additional Highlights

Storage Choice

12 Gb SAS for balanced cost-per-GB, or blistering NVMe for ultra-low latency—mix them in the same chassis to fine-tune performance, capacity and budget.

Processor Flexibility

Supports the full Intel Xeon Scalable stack (Bronze, Silver, Gold, Platinum) so you can right-size compute from entry file serving all the way to real-time analytics.

Memory at TB Scale

Up to 3 TB of DDR4 SmartMemory plus HPE Persistent Memory means huge in-memory databases without the cold-start penalty.

Model Variants

8-Bay SFF  ·  8 × 2.5 in

Dual 2nd-Gen Intel Xeon Scalable, 3 × PCIe slots, 24 RDIMM slots and embedded 4 × 1 GbE.

16-Bay SFF  ·  16 × 2.5 in

Six PCIe slots, redundant PSUs, 4 × 1 GbE NIC and full NVMe readiness for tier-0 storage.

12-Bay LFF  ·  12 × 3.5 in

High-capacity 3.5-inch HDD support for backup targets, media archives and large data lakes.

24-Bay SFF  ·  24 × 2.5 in

Maximum drive density in 2U—perfect for mixed NVMe/SAS flash tiers or virtualisation clusters.

In-Stock Wholesale: Server Hardware, Memory & Drives.

REQUEST A QUOTE